The Pathology of Breast Cancer

When reporting on a breast carcinoma specimen, it is required that reporting be done giving information about several different aspects (1) . It is easy to be overwhelmed with the histopathology data. The mnemonic “STINGER.COM” is meant as an aide memoire regarding the key things to be reported on.

 

Size in mm of index invasive tumour

 

Type / Total size

Type i.e. Ductal, Lobular etc

Total size of tumour i.e. Invasive + DCIS

 

Invasion (Lymphovascular) i.e Absent/Present

 

Nodes (involvement) e.g 0/2, 2/5 etc

 

Grade i.e. 1,2 or 3

 

Extent i.e. Localised, Multifocal, Multicentric etc

 

Receptors

ER e.g 0/8,8/8 etc

PR e.g 0/8,8/8 etc

HER 2 status

FISH status

 

 

 

Carcinoma in situ

Absent/present

Size in mm

Type i.e. DCIS,LCIS etc

 

Other pathology

Absent/Present

Type i.e. Paget’s, Atypical Ductal Hyperplasia etc

 

Margins/Microinvasion

Margins i.e. distance of disease from closest relevant margin

Microinvasion Absent/Present

 

 

Reference:

(1) Ellis I, Al-Sam S, Anderson N, Carder P, Deb R, Girling A, et al. Pathology reporting of breast disease in surgical excision specimens incorporating the dataset for histological reporting of breast cancer June 2016. 2016.